Malignant neoplasm of liver and intrahepatic bile ducts

C3_LIVER_INTRAHEPATIC_BILE_DUCTS

liver neoplasm: A benign or malignant epithelial neoplasm that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of benign epithelial neoplasms include hepatocellular adenoma and intrahepatic bile duct adenoma. Representative examples of malignant epithelial neoplasms include hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Cause of death: ICD-10 C22
Cause of death: ICD-9 155
Cause of death: ICD-8 155
Cancer registry: Topography ICD-O-3 C22

541

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

541

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Check minimum number of events None

541

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Include endpoints None

541

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C3_LIVER_INTRAHEPATIC_BILE_DUCTS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 518 101 417
Unadjusted prevalence (%) 0.17 0.06 0.31
Mean age at first event (years) 70.50 68.04 71.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_LIVER_INTRAHEPATIC_BILE_DUCTS – Malignant neoplasm of liver and intrahepatic bile ducts
GWS hits: 2

Survival analyses between endpoints

Plot

before Malignant neoplasm of liver and intrahepatic bile ducts
after Malignant neoplasm of liver and intrahepatic bile ducts

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Drugs most likely to be purchased after Malignant neoplasm of liver and intrahepatic bile ducts