Malignant neoplasm of corpus uteri

C3_CORPUS_UTERI

endometrial carcinoma: A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Cause of death: ICD-10 C54

Cause of death: ICD-9 182

Cause of death: ICD-8 1820

Cancer registry: Topography ICD-O-3 C54

1627

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

1627

Check minimum number of events None

1627

Include endpoints None

1627

C3_CORPUS_UTERI

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of corpus uteri based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1580	1580	-
Unadjusted prevalence (%)	0.51	0.91	-
Mean age at first event (years)	63.77	63.77	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.28 [1.43, 3.64]	5.6e-4	217
15 years	0.01	1.06 [0.72, 1.56]	7.6e-1	76
5 years	0.00	2.80 [1.86, 4.20]	6.8e-7	65
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_CORPUS_UTERI – Malignant neoplasm of corpus uteri
GWS hits: 0

Survival analyses between endpoints

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Plot

before Malignant neoplasm of corpus uteri
after Malignant neoplasm of corpus uteri

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Table

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Drugs most likely to be purchased after Malignant neoplasm of corpus uteri

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