Malignant neoplasm of cervix uteri

C3_CERVIX_UTERI

cervical carcinoma: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Cause of death: ICD-10 C53
Cause of death: ICD-9 180
Cause of death: ICD-8 180
Cancer registry: Topography ICD-O-3 C53

2722

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

2722

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Check minimum number of events None

2722

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Include endpoints None

2722

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C3_CERVIX_UTERI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 2615 2615 -
Unadjusted prevalence (%) 0.85 1.51 -
Mean age at first event (years) 37.78 37.78 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.11 [0.71, 1.74] 6.4e-1 109
15 years 0.00 0.52 [0.31, 0.86] 1.2e-2 32
5 years 0.00 1.99 [1.25, 3.16] 3.8e-3 31
1 year 0.00 3.21 [1.59, 6.49] 1.2e-3 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_CERVIX_UTERI – Malignant neoplasm of cervix uteri
GWS hits: 1

Survival analyses between endpoints

Plot

before Malignant neoplasm of cervix uteri
after Malignant neoplasm of cervix uteri

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Drugs most likely to be purchased after Malignant neoplasm of cervix uteri