Malignant neoplasm of breast, HER-positive

PheWeb

C3_BREAST_HERPLUS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions

RX_HERPLUS

7863

Filter registries

Cause of death: ICD-10 C50

Cause of death: ICD-9 174

Cause of death: ICD-8 174

Cancer registry: Topography ICD-O-3 C50

7432

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

7432

Check minimum number of events None

7432

Include endpoints None

7432

C3_BREAST_HERPLUS

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Malignant neoplasm of breast, HER-positive based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7222	7222	-
Unadjusted prevalence (%)	2.34	4.16	-
Mean age at first event (years)	59.01	59.01	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.80 [1.31, 2.46]	2.8e-4	521
15 years	0.01	1.38 [1.05, 1.81]	2.0e-2	283
5 years	0.00	2.31 [1.77, 3.01]	6.8e-10	164
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_BREAST_HERPLUS – Malignant neoplasm of breast, HER-positive
GWS hits: 20

Survival analyses between endpoints

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Plot

before Malignant neoplasm of breast, HER-positive
after Malignant neoplasm of breast, HER-positive

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Table

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Drugs most likely to be purchased after Malignant neoplasm of breast, HER-positive

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