Malignant neoplasm of breast, HER-positive

C3_BREAST_HERPLUS

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions

RX_HERPLUS

7863

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Filter registries

Cause of death: ICD-10 C50
Cause of death: ICD-9 174
Cause of death: ICD-8 174
Cancer registry: Topography ICD-O-3 C50

7432

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

7432

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Check minimum number of events None

7432

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Include endpoints None

7432

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C3_BREAST_HERPLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
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Number of individuals
7222 7222 -
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Unadjusted prevalence (%)
2.34 4.16 -
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Mean age at first event (years)
59.01 59.01 -

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Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.80 [1.31, 2.46] 2.8e-4 521
15 years 0.01 1.38 [1.05, 1.81] 2.0e-2 283
5 years 0.00 2.31 [1.77, 3.01] 6.8e-10 164
1 year - - - -

Age distribution of first events

01020304050607080900.0k0.2k0.4k0.6k0.8k1.0k1.2k1.4k1.6k1.8k2.0k2.2kageindividuals

Year distribution of first events

1980198519901995200020052010201520210.0k0.2k0.4k0.6k0.8k1.0k1.2k1.4k1.6k1.8k2.0k2.2k2.4k2.6k2.8kyearindividuals

Cumulative Incidence

Correlations

Index endpoint: C3_BREAST_HERPLUS – Malignant neoplasm of breast, HER-positive
GWS hits: 20

Survival analyses between endpoints

Plot

before Malignant neoplasm of breast, HER-positive
after Malignant neoplasm of breast, HER-positive

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Drugs most likely to be purchased after Malignant neoplasm of breast, HER-positive