Malignant neoplasm of anus and anal canal

C3_ANUS_ANALCANAL

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Cause of death: ICD-10 C21
Cause of death: ICD-9 154[2-3]
Cause of death: ICD-8 1542
Cancer registry: Topography ICD-O-3 C21

86

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

86

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Check minimum number of events None

86

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Include endpoints None

86

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C3_ANUS_ANALCANAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 80 50 30
Unadjusted prevalence (%) 0.03 0.03 0.02
Mean age at first event (years) 62.99 60.61 66.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: C3_ANUS_ANALCANAL – Malignant neoplasm of anus and anal canal
GWS hits: 0

Survival analyses between endpoints

Plot

before Malignant neoplasm of anus and anal canal
after Malignant neoplasm of anus and anal canal

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Drugs most likely to be purchased after Malignant neoplasm of anus and anal canal