Protozoal diseases

AB1_PROTOZOAL

toxoplasmosis: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 B50-B64
Hospital discharge: ICD-9 08[4-6]|130|136[3-4]|0889
Hospital discharge: ICD-8 08[6-7]|130|084|13601
Cause of death: ICD-10 B50-B64
Cause of death: ICD-9 08[4-6]|130|136[3-4]|0889
Cause of death: ICD-8 08[6-7]|130|084|13601

536

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

-

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Check minimum number of events None

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AB1_PROTOZOAL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 495 263 232
Unadjusted prevalence (%) 0.16 0.15 0.17
Mean age at first event (years) 49.73 46.56 53.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.44 [3.37, 12.32] 1.7e-8 61
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AB1_PROTOZOAL – Protozoal diseases
GWS hits: 0

Survival analyses between endpoints

Plot

before Protozoal diseases
after Protozoal diseases

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Drugs most likely to be purchased after Protozoal diseases