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Other spirochaetal diseases

DOIDEFOMESH PheWeb

AB1_OTHER_SPIROCHAETAL

Pinta: An infectious disease of the skin caused by Treponema carateum that occurs only in the western hemisphere. Age of onset is between 10 and 20 years of age. This condition is characterized by marked changes in the skin color and is believed to be transmitted by direct person-to-person contact.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 A65-A69
Hospital discharge: ICD-9 104|08[7-7]
Hospital discharge: ICD-8 08[8-9]
Cause of death: ICD-10 A65-A69
Cause of death: ICD-9 104|08[7-7]
Cause of death: ICD-8 08[8-9]

1773

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints

1773

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AB1_OTHER_SPIROCHAETAL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1715 1036 679
Unadjusted prevalence (%) 0.56 0.60 0.50
Mean age at first event (years) 54.65 52.54 57.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.83 [0.98, 3.39] 5.6e-2 64
15 years 0.01 1.21 [0.65, 2.24] 5.5e-1 31
5 years 0.00 1.96 [0.96, 4.01] 6.5e-2 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_OTHER_SPIROCHAETAL – Other spirochaetal diseases
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other spirochaetal diseases
after Other spirochaetal diseases

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Drugs most likely to be purchased after Other spirochaetal diseases

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