Late syphilis

PheWeb

AB1_LATE_SYPHILIS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 A52

Hospital discharge: ICD-9 09[2-6]

Hospital discharge: ICD-8 09[2-6]

Cause of death: ICD-10 A52

Cause of death: ICD-9 09[2-6]

Cause of death: ICD-8 09[2-6]

274

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

274

Check minimum number of events None

274

Include endpoints None

274

AB1_LATE_SYPHILIS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Late syphilis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	260	103	157
Unadjusted prevalence (%)	0.08	0.06	0.12
Mean age at first event (years)	52.90	51.25	53.99

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.13	10.50 [4.59, 24.00]	2.5e-8	36
15 years	0.02	3.91 [1.73, 8.84]	1.1e-3	13
5 years	0.01	12.22 [5.95, 25.11]	9.4e-12	16
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_LATE_SYPHILIS – Late syphilis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Late syphilis
after Late syphilis

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Table

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Drugs most likely to be purchased after Late syphilis

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