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Intestinal infectious diseases

DOIDEFOMESH PheWeb

AB1_INTESTINAL_INFECTIONS

amebiasis: A parasitic protozoa infectious disease that involves infection caused by the amoeba Entamoeba histolytica. Amebic invasion of the intestinal lining causes dysentery, colitis or diarrhea. The infection can also spread through the blood to the liver and, rarely, to the lungs, brain or other organs.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 A00-A09
Hospital discharge: ICD-9 00[1-9]
Hospital discharge: ICD-8 00[0-9]
Cause of death: ICD-10 A00-A09
Cause of death: ICD-9 00[1-9]
Cause of death: ICD-8 00[0-9]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints

33278

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AB1_INTESTINAL_INFECTIONS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Intestinal infectious diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 32026 17544 14482
Unadjusted prevalence (%) 10.38 10.11 10.73
Mean age at first event (years) 39.82 39.30 40.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.21 [2.82, 3.66] 1.5e-68 3833
15 years 0.01 1.46 [1.28, 1.66] 9.1e-9 1260
5 years 0.00 3.82 [3.43, 4.26] <1e-100 1300
1 year 0.00 10.96 [9.61, 12.50] <1e-100 864

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_INTESTINAL_INFECTIONS – Intestinal infectious diseases
GWS hits: 0

Survival analyses between endpoints

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Plot

before Intestinal infectious diseases
after Intestinal infectious diseases

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Drugs most likely to be purchased after Intestinal infectious diseases

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