Heartburn

MESH PheWeb

R18_HEARTBURN

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R12

Cause of death: ICD-10 R12

2024

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2024

Check minimum number of events None

2024

Include endpoints None

2024

R18_HEARTBURN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R1

Name in latin Pyrosis

Similar endpoints

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List of similar endpoints to Heartburn based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1916	1179	737
Unadjusted prevalence (%)	0.62	0.68	0.55
Mean age at first event (years)	56.86	55.81	58.53

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.28 [1.35, 3.85]	2.2e-3	111
15 years	0.01	0.81 [0.46, 1.46]	4.9e-1	35
5 years	0.00	2.45 [1.28, 4.69]	6.8e-3	52
1 year	0.00	5.84 [2.96, 11.51]	3.5e-7	23

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_HEARTBURN – Heartburn
GWS hits: 0

Survival analyses between endpoints

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Plot

before Heartburn
after Heartburn

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Heartburn

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