Retinopathy of prematurity

H7_RETINOPATPREMAT

retinopathy of prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H35.1

Hospital discharge: ICD-9 3622A

Hospital discharge: ICD-8 37704

Cause of death: ICD-10 H35.1

Cause of death: ICD-9 3622A

Cause of death: ICD-8 37704

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

H7_RETINOPATPREMAT

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H35

Name in latin Retinopathia praematuritatis

Similar endpoints

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List of similar endpoints to Retinopathy of prematurity based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	70	42	28
Unadjusted prevalence (%)	0.02	0.02	0.02
Mean age at first event (years)	36.12	40.29	29.86

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINOPATPREMAT – Retinopathy of prematurity
GWS hits:

Survival analyses between endpoints

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Plot

before Retinopathy of prematurity
after Retinopathy of prematurity

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Table

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Drugs most likely to be purchased after Retinopathy of prematurity

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