Separation of retinal layers (serosa)

H7_RETINASEPAR

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H35.7

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H35.7

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

835

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

835

Check minimum number of events None

835

Include endpoints None

835

H7_RETINASEPAR

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H35

Name in latin Separatio stratorum retinae

Similar endpoints

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List of similar endpoints to Separation of retinal layers (serosa) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	812	304	508
Unadjusted prevalence (%)	0.26	0.18	0.38
Mean age at first event (years)	53.91	54.92	53.30

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.24 [0.52, 2.96]	6.2e-1	29
15 years	0.01	0.94 [0.37, 2.41]	9.0e-1	20
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINASEPAR – Separation of retinal layers (serosa)
GWS hits: 0

Survival analyses between endpoints

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Plot

before Separation of retinal layers (serosa)
after Separation of retinal layers (serosa)

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Table

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Drugs most likely to be purchased after Separation of retinal layers (serosa)

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