Use of antiglaucoma preparations and miotics

DOID EFO MESH SNOMED PheWeb

H7_GLAUCOMAMEDICATION

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC S01EA

3308

Check pre-conditions, main-only, mode, ICD version None

1912

Check minimum number of events

Min. number of events 3

1912

Include endpoints None

1912

H7_GLAUCOMAMEDICATION

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Use of antiglaucoma preparations and miotics based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1842	1022	820
Unadjusted prevalence (%)	0.60	0.59	0.61
Mean age at first event (years)	65.45	64.93	66.10

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.25 [0.83, 1.88]	2.9e-1	385
15 years	0.01	0.96 [0.69, 1.34]	8.2e-1	224
5 years	0.00	1.47 [1.11, 1.96]	7.9e-3	107
1 year	0.00	0.93 [0.52, 1.68]	8.1e-1	13

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCOMAMEDICATION – Use of antiglaucoma preparations and miotics
GWS hits: 2

Survival analyses between endpoints

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Plot

before Use of antiglaucoma preparations and miotics
after Use of antiglaucoma preparations and miotics

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Table

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Drugs most likely to be purchased after Use of antiglaucoma preparations and miotics

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