Primary angle-closure glaucoma

H7_GLAUCCLOSEPRIM

primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.2

Hospital discharge: ICD-9 3652

Hospital discharge: ICD-8 37500|37511

Cause of death: ICD-10 H40.2

Cause of death: ICD-9 3652

Cause of death: ICD-8 37500|37511

943

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

943

Check minimum number of events None

943

Include endpoints None

943

H7_GLAUCCLOSEPRIM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H40

Name in latin Glaucoma congestivum primarium

Similar endpoints

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List of similar endpoints to Primary angle-closure glaucoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	905	544	361
Unadjusted prevalence (%)	0.29	0.31	0.27
Mean age at first event (years)	63.86	63.79	63.97

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.94 [1.03, 3.65]	3.9e-2	172
15 years	0.01	1.16 [0.73, 1.86]	5.3e-1	78
5 years	0.00	2.12 [1.41, 3.19]	2.9e-4	50
1 year	0.00	2.25 [1.17, 4.33]	1.5e-2	11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma
GWS hits: 0

Survival analyses between endpoints

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Plot

before Primary angle-closure glaucoma
after Primary angle-closure glaucoma

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Table

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Drugs most likely to be purchased after Primary angle-closure glaucoma

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