Chorioretinal inflammation

H7_CHORIORETINFLAM

pars planitis: Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H30, H32.0*, H32.0*A18.5, H32.0*A52.79, H32.0*A69.2, H32.0*B58.0

Hospital discharge: ICD-9 363[0-2]

Hospital discharge: ICD-8 365|36700

Cause of death: ICD-10 H30, H32.0*, H32.0*A18.5, H32.0*A52.79, H32.0*A69.2, H32.0*B58.0

Cause of death: ICD-9 363[0-2]

Cause of death: ICD-8 365|36700

1561

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

589

Check minimum number of events None

589

Include endpoints None

589

H7_CHORIORETINFLAM

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF6

Similar endpoints

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List of similar endpoints to Chorioretinal inflammation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	569	334	235
Unadjusted prevalence (%)	0.18	0.19	0.17
Mean age at first event (years)	45.79	44.07	48.23

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.93 [0.69, 5.43]	2.1e-1	48
15 years	0.01	1.34 [0.52, 3.49]	5.5e-1	19
5 years	0.00	4.13 [1.82, 9.39]	7.0e-4	14
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_CHORIORETINFLAM – Chorioretinal inflammation
GWS hits: 2

Survival analyses between endpoints

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Plot

before Chorioretinal inflammation
after Chorioretinal inflammation

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Table

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Drugs most likely to be purchased after Chorioretinal inflammation

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