Background retinopathy and retinal vascular changes

H7_BCKRNDRETINOPAT

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H35.0

Hospital discharge: ICD-9 3621|3624A

Hospital discharge: ICD-8 36701|37705|37709|37712

Cause of death: ICD-10 H35.0

Cause of death: ICD-9 3621|3624A

Cause of death: ICD-8 36701|37705|37709|37712

436

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

436

Check minimum number of events None

436

Include endpoints None

436

H7_BCKRNDRETINOPAT

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF6

Parent code in ICD-10 H35

Name in latin Retinopathia recessualis et commutationes vasculares retinae

Similar endpoints

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List of similar endpoints to Background retinopathy and retinal vascular changes based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	416	194	222
Unadjusted prevalence (%)	0.13	0.11	0.16
Mean age at first event (years)	54.89	55.72	54.17

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.89 [1.41, 5.95]	3.9e-3	63
15 years	0.01	1.59 [0.70, 3.62]	2.7e-1	29
5 years	0.00	3.55 [1.77, 7.12]	3.7e-4	20
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_BCKRNDRETINOPAT – Background retinopathy and retinal vascular changes
GWS hits: 1

Survival analyses between endpoints

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Plot

before Background retinopathy and retinal vascular changes
after Background retinopathy and retinal vascular changes

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Table

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Drugs most likely to be purchased after Background retinopathy and retinal vascular changes

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