Anorexia (incl.atypical)

F5_ANOREX

anorexia nervosa: A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F50.0, F50.1
Hospital discharge: ICD-9 7830A|3071A
Hospital discharge: ICD-8 784
Cause of death: ICD-10 F50.0, F50.1
Cause of death: ICD-9 7830A|3071A
Cause of death: ICD-8 784

4027

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1547

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Check minimum number of events None

1547

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Include endpoints None

1547

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F5_ANOREX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1489 1168 321
Unadjusted prevalence (%) 0.48 0.67 0.24
Mean age at first event (years) 22.96 21.98 26.56

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.52 [0.63, 3.66] 3.5e-1 84
15 years 0.01 0.80 [0.37, 1.74] 5.7e-1 27
5 years 0.00 2.58 [1.33, 5.04] 5.3e-3 21
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_ANOREX – Anorexia (incl.atypical)
GWS hits: 0

Survival analyses between endpoints

Plot

before Anorexia (incl.atypical)
after Anorexia (incl.atypical)

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Drugs most likely to be purchased after Anorexia (incl.atypical)