Polycystic ovarian syndrome, concortium definition

PheWeb

E4_PCOS_CONCORTIUM

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule

Sex only females

180574

Check conditions None

180574

Filter registries

Hospital Discharge: ICD-10 L68.0#, N92.5, N92.6

Hospital discharge: ICD-9 626|7041

Hospital discharge: ICD-8 626|70405

Hospital discharge: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74

Hospital discharge: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940

Hospital discharge: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

Cause of death: ICD-10 L68.0#, N92.5, N92.6

Cause of death: ICD-9 626|7041

Cause of death: ICD-8 626|70405

Cause of death: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74

Cause of death: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940

Cause of death: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints

E4_PCOS

N14_MENSIRREG

26010

E4_PCOS_CONCORTIUM

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Polycystic ovarian syndrome, concortium definition based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	25117	25117	-
Unadjusted prevalence (%)	8.14	14.47	-
Mean age at first event (years)	38.55	38.55	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.55 [0.47, 0.63]	5.1e-16	1359
15 years	0.00	0.42 [0.36, 0.48]	9.6e-32	574
5 years	0.00	0.31 [0.25, 0.40]	3.7e-21	85
1 year	0.00	0.34 [0.21, 0.57]	3.6e-5	16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_PCOS_CONCORTIUM – Polycystic ovarian syndrome, concortium definition
GWS hits:

Survival analyses between endpoints

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Plot

before Polycystic ovarian syndrome, concortium definition
after Polycystic ovarian syndrome, concortium definition

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Table

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Drugs most likely to be purchased after Polycystic ovarian syndrome, concortium definition

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