Leukaemia of unspecified cell type

CD2_LEUKAEMIA_NAS

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 C95

Hospital discharge: ICD-9 20[7-8]

Hospital discharge: ICD-8 207

Hospital discharge: excluded ICD-9 207[0-8]

Hospital discharge: excluded ICD-8 207[0-2]

Cause of death: ICD-10 C95

Cause of death: ICD-9 20[7-8]

Cause of death: ICD-8 207

Cause of death: excluded ICD-9 207[0-8]

Cause of death: excluded ICD-8 207[0-2]

202

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

182

Check minimum number of events None

182

Include endpoints None

182

CD2_LEUKAEMIA_NAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 C81-C96

Name in latin Leuc(h)aemiae typo cellulari non specificato

Similar endpoints

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List of similar endpoints to Leukaemia of unspecified cell type based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	162	74	88
Unadjusted prevalence (%)	0.05	0.04	0.07
Mean age at first event (years)	54.56	50.81	57.71

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_LEUKAEMIA_NAS – Leukaemia of unspecified cell type
GWS hits: 0

Survival analyses between endpoints

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Plot

before Leukaemia of unspecified cell type
after Leukaemia of unspecified cell type

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Table

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Drugs most likely to be purchased after Leukaemia of unspecified cell type

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