Malignant neoplasm of anus and anal canal

C3_ANUS_ANALCANAL

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Cause of death: ICD-10 C21

Cause of death: ICD-9 154[2-3]

Cause of death: ICD-8 1542

Cancer registry: Topography ICD-O-3 C21

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

C3_ANUS_ANALCANAL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Malignant neoplasm of anus and anal canal based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	80	50	30
Unadjusted prevalence (%)	0.03	0.03	0.02
Mean age at first event (years)	62.99	60.61	66.97

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_ANUS_ANALCANAL – Malignant neoplasm of anus and anal canal
GWS hits: 0

Survival analyses between endpoints

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Plot

before Malignant neoplasm of anus and anal canal
after Malignant neoplasm of anus and anal canal

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Table

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Drugs most likely to be purchased after Malignant neoplasm of anus and anal canal

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