IBD co-morbidities, not ICD-10 XI

PheWeb

IBD_COMORB

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

NEURODIS

N14_ENDOMETRIOSIS

IBD_INFECTIONS

IBD_PULM

THYROID_DISORDER_IBD

DM_IBD

M13_MUSCULOSKELETAL

N14_GLOMERULAR

IBD_VIRAL_HEPATITIS

234197

IBD_COMORB

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to IBD co-morbidities, not ICD-10 XI based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	226195	125951	100244
Unadjusted prevalence (%)	73.31	72.58	74.24
Mean age at first event (years)	44.71	42.64	47.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	2.63 [2.45, 2.82]	<1e-100	22495
15 years	0.01	1.64 [1.52, 1.77]	7.6e-36	10615
5 years	0.00	2.54 [2.33, 2.76]	<1e-100	4262
1 year	0.00	6.07 [5.25, 7.02]	<1e-100	1959

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: IBD_COMORB – IBD co-morbidities, not ICD-10 XI
GWS hits:

Survival analyses between endpoints

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Plot

before IBD co-morbidities, not ICD-10 XI
after IBD co-morbidities, not ICD-10 XI

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Table

Loading survival analyses table

Drugs most likely to be purchased after IBD co-morbidities, not ICD-10 XI

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