Glaucoma secondary to other eye disorders

H7_GLAUCSECDISEASE

open-angle glaucoma: Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.5

Hospital discharge: ICD-9 3655|3656A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H40.5

Cause of death: ICD-9 3655|3656A

Cause of death: ICD-8 $!$

884

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

884

Check minimum number of events None

884

Include endpoints None

884

H7_GLAUCSECDISEASE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H40

Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Similar endpoints

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List of similar endpoints to Glaucoma secondary to other eye disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	845	386	459
Unadjusted prevalence (%)	0.27	0.22	0.34
Mean age at first event (years)	60.09	57.15	62.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.58 [0.64, 3.91]	3.2e-1	167
15 years	0.01	1.01 [0.49, 2.09]	9.8e-1	68
5 years	0.00	3.10 [1.96, 4.90]	1.3e-6	69
1 year	0.00	4.25 [2.42, 7.46]	4.5e-7	20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCSECDISEASE – Glaucoma secondary to other eye disorders
GWS hits: 0

Survival analyses between endpoints

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Plot

before Glaucoma secondary to other eye disorders
after Glaucoma secondary to other eye disorders

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Table

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Drugs most likely to be purchased after Glaucoma secondary to other eye disorders

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