Glaucoma, exfoliation

DOID EFO MESH SNOMED PheWeb

H7_GLAUCOMA_XFG

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H40.10

Hospital discharge: ICD-9 3651B

Hospital discharge: ICD-8 37512

Cause of death: ICD-10 H40.10

Cause of death: ICD-9 3651B

Cause of death: ICD-8 37512

2424

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2424

Check minimum number of events None

2424

Include endpoints None

2424

H7_GLAUCOMA_XFG

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF4

Parent code in ICD-10 H401

Name in latin Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Similar endpoints

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List of similar endpoints to Glaucoma, exfoliation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2314	1331	983
Unadjusted prevalence (%)	0.75	0.77	0.73
Mean age at first event (years)	70.63	70.36	70.98

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.97 [0.61, 1.55]	9.1e-1	474
15 years	0.00	0.77 [0.54, 1.10]	1.5e-1	275
5 years	0.00	1.12 [0.84, 1.49]	4.6e-1	118
1 year	0.00	1.56 [1.03, 2.36]	3.7e-2	31

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 2

Survival analyses between endpoints

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Plot

before Glaucoma, exfoliation
after Glaucoma, exfoliation

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Table

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Drugs most likely to be purchased after Glaucoma, exfoliation

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